Lichen sclerosus

  title={Lichen sclerosus},
  author={P D Yesudian and H Sugunendran and C M Bates and C O'Mahony},
  journal={International Journal of STD \& AIDS},
  pages={465 - 474}
Lichen sclerosus (LS) is a chronic inflammatory disorder of the skin and mucosa, presenting to genitourinary physicians and dermatologists. It affects both sexes and all age groups. Although the exact aetiology is uncertain, genetic predisposition, infections and autoimmune factors have been implicated in its pathogenesis. Symptoms include pruritis and soreness, but asymptomatic presentations are not uncommon. The classical clinical picture is of atrophic white plaques in the anogenital region… Expand
10 Citations
Medical and Surgical Management of Genital Lichen Sclerosus
The etiology, clinical presentation, and management options for genital LS are discussed, and various reconstructive techniques may be used depending on patient symptoms, extent of involvement, and the location of disease. Expand
Lichen Sclerosus et Atrophicus Induced by Carbamazepine: A Case Report
A case of Lichen Sclerosus in a 73-year-old man who had been treated for epilepsy with carbamazepine is reported, believed to be the first report of a Lichen sclerosUS et atrophicus induced by carbamazepsine. Expand
Treatment of genital lichen sclerosus with topical calcipotriol
The antibody studies of the patients’ blood performed at the South West Regional HPA laboratory, Bristol, showed a high titre to L2 (C. trachomatis) compatible with recent LGV infection, which may need to be reconsidered as LGV might be missed. Expand
Fat Grafting Improves Fibrosis and Scarring in Vulvar Lichen Sclerosus: Results From a Prospective Cohort Study
The use of fat grafting in lichen sclerosus is promising and further studies are required to rule out a potential placebo effect and to better understand the underlying molecular mechanism of action. Expand
Clitoral Phimosis: Effects on Female Sexual Function and Surgical Treatment Outcomes.
The results of this study will help clinicians to centralize treatment methods and advise patients on the management of clitoral phimosis and postoperative results of sexual function, distress, and satisfaction with genitalia in women with severe CP are evaluated, using validated questionnaires. Expand
Development and Validation of a Clinical Grading Scale to Assess the Vulvar Region: The Vulvar Architecture Severity Scale.
The Vulvar Architecture Severity Scale (VASS) is a reliable scale to assess the severity of VLS, and it might be considered as an outcome measure in future VLS trials. Expand
Why no accessible condom-vending machines in UK high streets?
  • S. Green
  • Medicine
  • International journal of STD & AIDS
  • 2005
It is suggested that an integral part of the long-term follow-up management of patients with lichen sclerosus be enquiry about sexual functioning and appropriate management of such problems, given the data available and experience. Expand
As dermatoses vulvares representam um grupo heterogeneo de doencas dermatologicas de caracter infeccioso, inflamatorio ou maligno, nomeadamente liquen escleroso, eczema, psoriase, liquen plano e vulvite de Zoon, que sao mais frequentes na mulher quando comparadas aos seus equivalentes no sexo masculino. Expand
Penis and Scrotum


Lichen sclerosus et atrophicus confined to the areolae
An unusual case in which involvement with LSA was localized to the areolae of a 26-year-old married female student, with asymptomatic, symmetrical lesions confined to the isoliic. Expand
Lichen sclerosus et atrophicus in children.
The symptoms, findings, associated conditions, and treatment of lichen sclerosus et atrophicus were studied in 10 girls and one boy and three patients at the ages of 9, 11, and 12 years. Expand
Management of anogenital lichen sclerosus
Lichen sclerosus (LS) is a skin condition that affects genital and extra genital epithelia in both males and females of all ages and it may occur in association with other autoimmune disease.Expand
Nail dystrophy due to lichen sclerosus?
This work reports two cases of LS with nail involvement, and reviews existing literature on nail disease in LS and discusses the possible aetiology of the nail changes. Expand
Lichen sclerosus.
Once considered primarily a surgical problem, especially when the genitals were involved, lichen sclerosus will respond to a variety of systemic and topical therapies. Expand
Histopathological and immunological studies in a cohort of balanitis xerotica obliterans.
Poor local hygiene, circumcision and association of auto-immune diseases like vitiligo are responsible as suggested in this study as well as some chronic antigenic stimulation. Expand
Lichen sclerosus et atrophicus in a vaccination site.
An unusual clinical presentation of verrucous hyperpigmented plaques is reported in a 13-year-old girl seen on May 21, 1975, for evaluation of her vaccination site. Expand
Eosinophilic infiltration in lichen sclerosus et atrophicus.
An observation is reported of eosinophils in the cellular infiltrate of lichen sclerosus et atrophicus (LSA), which occurred in an aged man, accompanied by variegated clinical features in an 88-year-old Japanese man, who had gradually developed a band-like sclerosed area around the abdomen. Expand
Lichen sclerosus et atrophicus and sexual abuse.
There was a high rate of coexisting sexual abuse with LSA, possibly due to genital trauma, and associations with trauma, autoimmunity, and infection were noted in this large series of paediatric LSA. Expand