Lichen planus remission is associated with a decrease of human herpes virus type 7 protein expression in plasmacytoid dendritic cells

@article{Vries2007LichenPR,
  title={Lichen planus remission is associated with a decrease of human herpes virus type 7 protein expression in plasmacytoid dendritic cells},
  author={Henry J. C. de Vries and Marcel B. M. Teunissen and Fokla Zorgdrager and Daisy I. Picavet and Marion Cornelissen},
  journal={Archives of Dermatological Research},
  year={2007},
  volume={299},
  pages={213 - 219}
}
The cause of lichen planus is still unknown. Previously we showed human herpes virus 7 (HHV-7) DNA and proteins in lesional lichen planus skin, and significantly less in non-lesional lichen planus, psoriasis or healthy skin. Remarkably, lesional lichen planus skin was infiltrated with plasmacytoid dendritic cells. If HHV-7 is associated with lichen planus, then HHV-7 replication would reduce upon lichen planus remission. HHV-7 DNA detection was performed by nested PCR and HHV-7 protein by… CONTINUE READING

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