Lhermitte-Duclos disease is a clinical manifestation of Cowden's syndrome.

@article{Vantomme2001LhermitteDuclosDI,
  title={Lhermitte-Duclos disease is a clinical manifestation of Cowden's syndrome.},
  author={Nikolaas Vantomme and Frank van Calenbergh and Jan Goffin and Rafa{\"e}l Sciot and Philippe Demaerel and Christian Plets},
  journal={Surgical neurology},
  year={2001},
  volume={56 3},
  pages={201-4; discussion 204-5}
}
BACKGROUND Lhermitte-Duclos disease (LDD) is a hamartomatous overgrowth of cerebellar ganglion cells, which replace granular cells and Purkinje cells. In recent years several cases involving the association between LDD and Cowden's syndrome (CS), an autosomal dominant condition characterized by multiple hamartomas and neoplastic lesions in skin and internal organs, have been reported. METHODS We reviewed the medical records and imaging studies of six patients with LDD who were treated at our… CONTINUE READING
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