Lgr5 Identifies Progenitor Cells Capable of Taste Bud Regeneration after Injury

@inproceedings{Takeda2013Lgr5IP,
  title={Lgr5 Identifies Progenitor Cells Capable of Taste Bud Regeneration after Injury},
  author={Norifumi Takeda and Rajan Jain and Deqiang Li and Li Li and Min Min Lu and Jonathan A. Epstein},
  booktitle={PloS one},
  year={2013}
}
Taste buds are composed of a variety of taste receptor cell types that develop from tongue epithelium and are regularly replenished under normal homeostatic conditions as well as after injury. The characteristics of cells that give rise to regenerating taste buds are poorly understood. Recent studies have suggested that Lgr5 (leucine-rich repeat-containing G-protein coupled receptor 5) identifies taste bud stem cells that contribute to homeostatic regeneration in adult circumvallate and foliate… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 24 REFERENCES