Levuglandin E2 crosslinks proteins.

@article{Iyer1989LevuglandinEC,
  title={Levuglandin E2 crosslinks proteins.},
  author={R. S. Iyer and S. Ghosh and R. G. Salomon},
  journal={Prostaglandins},
  year={1989},
  volume={37 4},
  pages={
          471-80
        }
}
Levuglandin E2 (LGE2), a gamma-ketoaldehyde produced by rearrangement of the prostaglandin endoperoxide PGH2 under the aqueous conditions of its biosynthesis, causes extensive intermolecular crosslinking of ovalbumin at pH 6 or pH 7 and 37 degrees C. The time dependence of protein oligomerization is monitored by SDS-PAGE. Effects of pH and concentration on the extent of LGE2-induced crosslinking are examined. The efficacy of LGE2 for inducing crosslinking is compared with other oxidative… Expand
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