Levothyroxin restores hypothyroidism-induced impairment of hippocampus-dependent learning and memory: Behavioral, electrophysiological, and molecular studies.

@article{Alzoubi2009LevothyroxinRH,
  title={Levothyroxin restores hypothyroidism-induced impairment of hippocampus-dependent learning and memory: Behavioral, electrophysiological, and molecular studies.},
  author={Karem H Alzoubi and Nashaat Z. Gerges and Abdulaziz Mohammed Aleisa and Karim A Alkadhi},
  journal={Hippocampus},
  year={2009},
  volume={19 1},
  pages={66-78}
}
Hypothyroidism induces cognitive impairment in experimental animals and patients. Clinical reports are conflicting about the ability of thyroid hormone replacement therapy to fully restore the hypothyroidism-induced learning and memory impairment. In this study, we investigated the effects of L-thyroxin (thyroxin) treatment on hippocampus-dependent learning and memory in thyroidectomized adult rats. In the radial arm water maze (RAWM) task, thyroxin treated thyroidectomized animals made… CONTINUE READING
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