Levosimendan for resuscitating the microcirculation in patients with septic shock: a randomized controlled study

@inproceedings{Morelli2010LevosimendanFR,
  title={Levosimendan for resuscitating the microcirculation in patients with septic shock: a randomized controlled study},
  author={Andrea Salas Morelli and Abele Donati and Christian Ertmer and Sebastian Rehberg and Matthias Lange and Alessandra Orecchioni and Valeria Cecchini and Giovanni Landoni and Paolo Pelaia and Paolo Pietropaoli and Hugo Van Aken and Jean-Louis Teboul and Can Ince and Martin Westphal},
  booktitle={Critical care},
  year={2010}
}
INTRODUCTION The purpose of the present study was to investigate microcirculatory blood flow in patients with septic shock treated with levosimendan as compared to an active comparator drug (i.e. dobutamine). The primary end point was a difference of ≥ 20% in the microvascular flow index of small vessels (MFIs) among groups. METHODS The study was designed as a prospective, randomized, double-blind clinical trial and performed in a multidisciplinary intensive care unit. After achieving… CONTINUE READING
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