Levosimendan for Ischemic Preconditioning in Thoracic Aortic Aneurysm Repair

@article{Ersoy2008LevosimendanFI,
  title={Levosimendan for Ischemic Preconditioning in Thoracic Aortic Aneurysm Repair},
  author={Ozgur Ersoy and Ali Baran Budak and Ufuk Mungan and Ufuk Tutun and Ali Parlar and Ferit Çiçekçioğlu and Ahmet Tulga Ulus and Salih Fehmi Katırcıoğlu},
  journal={Journal of Cardiac Surgery},
  year={2008},
  volume={23}
}
Abstract  Background and Aim: Postoperative neurologic deficit is the most devastating complication after surgical thoracic aorta repair. Cerebrospinal fluid drainage and some medications are used for spinal cord protection during and after the operation. Methods: A 25‐year‐old patient applied to our clinic with a traumatic descending aortic aneurysm. We performed a surgical repair for the aneurysm but could not achieve to place a lumbar catheter to provide cerebrospinal fluid drainage… 
3 Citations
Levosimendan in perioperative and critical care patients
TLDR
New practice advisories and proposals for indications to treat and prevent low-output syndrome in patients at risk are warranted for patients undergoing cardiac surgery with cardiopulmonary bypass and levosimendan should also be considered as an adjunct drug for the treatment of cardiogenic shock.
Perioperative use of levosimendan: best practice in operative settings.
TLDR
The active long-lived me-tabolite OR-1896, also an inodilator, shows-sensitizing effect in the cardiac myofilaments.

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