Levomilnacipran Extended Release: First Global Approval

@article{Hair2013LevomilnacipranER,
  title={Levomilnacipran Extended Release: First Global Approval},
  author={Philip I. Hair and Fiona Cameron and Karly P Garnock-jones},
  journal={Drugs},
  year={2013},
  volume={73},
  pages={1639-1645}
}
Pierre Fabre and Forest Laboratories are developing levomilnacipran extended release (ER) [FETZIMA™], an enantiomer of milnacipran, for the treatment of major depressive disorder (MDD). In addition, Pierre Fabre (the originator of the compound) is developing the drug to improve recovery in patients with ischaemic stroke. Levomilnacipran ER exerts its effects by selectively inhibiting the reuptake of norepinephrine and serotonin (two neurotransmitters known to play an essential role in… 
The Role of Levomilnacipran in the Management of Major Depressive Disorder: A Comprehensive Review
TLDR
Preliminary evidence suggests that levomilnacipran ER may be effective in improving not only depressive symptoms but also symptoms related to functioning (social life, work, and family life) in relation to currently available antidepressants including other SNRIs.
Novel drugs in depression - A new hope
TLDR
Agomelatine, vortioxetine, vilazodone, and levomilnacipran extended release (ER) having different mechanisms have been recently approved by the United States Food and Drug Administration.

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