Levofloxacin-induced photosensitivity mimicking severe cellulitis in a patient with diabetic foot infection

  title={Levofloxacin-induced photosensitivity mimicking severe cellulitis in a patient with diabetic foot infection},
  author={C. V. Loupa and Evangelia Meimeti and Eleftherios D. Voyatzoglou and Andriana Donou and Dimitrios Economou},
  journal={MOJ Clinical \& Medical Case Reports},
DFU complications are a significant source of morbidity and mortality. With appropriate wound care, off-loading and diabetic treatment regulation, DFU can heal. Osteomyelitis is one of the most common expression of diabetic foot infection and an important risk factor for minor or major lower-extremity amputation. The primary aim of treatment of diabetic foot problems is limb preservation. Thus, the administration of antibiotics for the treatment of osteomyelitis is mandatory [2]. 
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Structure-activity and structure-side-effect relationships for the quinolone antibacterials.
  • J. Domagala
  • Chemistry
    The Journal of antimicrobial chemotherapy
  • 1994
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  • Journal canadien des maladies infectieuses
  • 2002