Levodopa prolongs life expectancy and is non-toxic to substantia nigra.

  title={Levodopa prolongs life expectancy and is non-toxic to substantia nigra.},
  author={Azi H Rajput},
  journal={Parkinsonism & related disorders},
  volume={8 2},
  • Azi H Rajput
  • Published 2001 in Parkinsonism & related disorders
The primary objective of the study was to determine the effect of levodopa (LD) on human substantia nigra. The study included patients seen at the Movement Disorder Clinic, Saskatoon over a 32 year period. The evidence provided is based on epidemiological observations of 934 consecutive Parkinson syndrome (PS) patients assessed during 22 years and detailed studies of six patients including two autopsies. Life expectancy increased significantly with LD therapy. The prolonged survival was evident… CONTINUE READING


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