Levodopa: faster and better word learning in normal humans.

@article{Knecht2004LevodopaFA,
  title={Levodopa: faster and better word learning in normal humans.},
  author={Stefan Knecht and Caterina Breitenstein and Stefan Bushuven and Stefanie Wailke and Sandra Kamping and Agnes Fl{\"o}el and Pienie Zwitserlood and E Bernd Ringelstein},
  journal={Annals of neurology},
  year={2004},
  volume={56 1},
  pages={
          20-6
        }
}
Dopamine is a potent modulator of learning and has been implicated in the encoding of stimulus salience. Repetition, however, as required for the acquisition and reacquisition of sensorimotor or cognitive skills (e.g., in aphasia therapy), decreases salience. We here tested whether increasing brain levels of dopamine during repetitive training improves learning success. Forty healthy humans took 100mg of the dopamine precursor levodopa or placebo daily for 5 days in a randomized double-blind… CONTINUE READING

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