Levo-tetrahydropalmatine attenuates mouse blood-brain barrier injury induced by focal cerebral ischemia and reperfusion: Involvement of Src kinase

@inproceedings{Mao2015LevotetrahydropalmatineAM,
  title={Levo-tetrahydropalmatine attenuates mouse blood-brain barrier injury induced by focal cerebral ischemia and reperfusion: Involvement of Src kinase},
  author={Xiao-Wei Mao and Chun-shui Pan and Ping Huang and Yu-ying Liu and Chuan-She Wang and Li Yan and Bai-he Hu and Xin Chang and Ke He and Huan-Na Mu and Quan Li and Kai Sun and Jing-yu Fan and Jingyan Han},
  booktitle={Scientific reports},
  year={2015}
}
The restoration of blood flow following thrombolytic therapy causes ischemia and reperfusion (I/R) injury leading to blood-brain barrier (BBB) disruption and subsequent brain edema in patients of ischemic stroke. Levo-tetrahydropalmatine (l-THP) occurs in Corydalis genus and some other plants. However, whether l-THP exerts protective role on BBB disruption… CONTINUE READING