Levetiracetam in the treatment of Lennox-Gastaut syndrome.

  title={Levetiracetam in the treatment of Lennox-Gastaut syndrome.},
  author={Emily C de los Reyes and Gregory B. Sharp and Jane P Williams and Sue E Hale},
  journal={Pediatric neurology},
  volume={30 4},
Lennox-Gastaut syndrome is an epileptic encephalopathy characterized by multiple seizure types, mental retardation, and a slow spike-and-wave pattern on electroencephalography. Medical intractability is common. We identified a case series of six patients diagnosed with Lennox-Gastaut syndrome in which levetiracetam was initiated as add-on therapy for the management of seizures. At follow-up, four patients experienced 100% reduction of their myoclonic seizures; two patients had greater than 50… CONTINUE READING


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