Levetiracetam in children with refractory epilepsy: Lack of correlation between plasma concentration and efficacy

@article{Giroux2009LevetiracetamIC,
  title={Levetiracetam in children with refractory epilepsy: Lack of correlation between plasma concentration and efficacy},
  author={Patricia C. Giroux and Milagros Salas-Prato and Yves Th{\'e}{\^o}ret and Lionel Carmant},
  journal={Seizure},
  year={2009},
  volume={18},
  pages={559-563}
}
PURPOSE The goals of this study are to evaluate the efficacy and tolerability of levetiracetam (LEV) as add-on therapy in children with refractory epilepsies and to determine the value of LEV blood level monitoring in this population. METHODS Sixty-nine children (39 males and 30 females) treated with LEV between 2006 and 2007 were selected. Their medical files were reviewed for LEV efficacy and tolerability. In a subgroup of children currently taking LEV, plasma concentrations were determined… CONTINUE READING

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