• Corpus ID: 248722094

Leveraging isotopologues as a general strategy to image neurotransmitters with vibrational microscopy

  title={Leveraging isotopologues as a general strategy to image neurotransmitters with vibrational microscopy},
  author={Gabriel F. Dorlhiac and Markita P. Landry and Aaron M. Streets},
Chemical neurotransmission is central to neurotypical brain function but also implicated in a variety of psychiatric and neurodegenerative diseases. The release dynamics of neurotransmitters is correlated with but distinct from electrical signal propagation. It is therefore necessary to track neurotransmitter modulation separately from electrical activity. Here, we present a new approach for imaging deuterated neurotransmitter molecules with vibrational microscopy in the cell-silent window… 

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