Leveraging cancer genome information in hematologic malignancies.

@article{Rampal2013LeveragingCG,
  title={Leveraging cancer genome information in hematologic malignancies.},
  author={Raajit K Rampal and Ross L. Levine},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2013},
  volume={31 15},
  pages={
          1885-92
        }
}
The use of candidate gene and genome-wide discovery studies in the last several years has led to an expansion of our knowledge of the spectrum of recurrent, somatic disease alleles, which contribute to the pathogenesis of hematologic malignancies. Notably, these studies have also begun to fundamentally change our ability to develop informative prognostic schema that inform outcome and therapeutic response, yielding substantive insights into mechanisms of hematopoietic transformation in… CONTINUE READING

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