Leveraging Multilayered “Omics” Data for Atopic Dermatitis: A Road Map to Precision Medicine

  title={Leveraging Multilayered “Omics” Data for Atopic Dermatitis: A Road Map to Precision Medicine},
  author={Debajyoti Ghosh and Jonathan A. Bernstein and Gurjit K. Khurana Hershey and Marc E. Rothenberg and Tesfaye B. Mersha},
  journal={Frontiers in Immunology},
Atopic dermatitis (AD) is a complex multifactorial inflammatory skin disease that affects ~280 million people worldwide. About 85% of AD cases begin in childhood, a significant portion of which can persist into adulthood. Moreover, a typical progression of children with AD to food allergy, asthma or allergic rhinitis has been reported (“allergic march” or “atopic march”). AD comprises highly heterogeneous sub-phenotypes/endotypes resulting from complex interplay between intrinsic and extrinsic… 

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  • Biology, Medicine
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  • 2016
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