Levels of semenogelin in human spermatozoa decrease during capacitation: involvement of reactive oxygen species and zinc.

Abstract

BACKGROUND Semenogelin (Sg), the main protein of human semen coagulum, prevents sperm capacitation. The objective of this study was to examine the role of Sg and its mechanism of action. METHODS AND RESULTS Sg blocked sperm capacitation triggered by various stimuli, via inhibition of superoxide anion (O(2)*-; luminescence assay) and nitric oxide (NO… (More)
DOI: 10.1093/humrep/deq110

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@article{Lamirande2010LevelsOS, title={Levels of semenogelin in human spermatozoa decrease during capacitation: involvement of reactive oxygen species and zinc.}, author={Eve de Lamirande and Genevi{\`e}ve Lamothe}, journal={Human reproduction}, year={2010}, volume={25 7}, pages={1619-30} }