Levels of estrogen receptors alpha and beta in frontal cortex of patients with Alzheimer's disease: relationship to Mini-Mental State Examination scores.

@article{Kelly2008LevelsOE,
  title={Levels of estrogen receptors alpha and beta in frontal cortex of patients with Alzheimer's disease: relationship to Mini-Mental State Examination scores.},
  author={Jeremiah F. Kelly and Julia L. Bienias and Avni Shah and Kathleen A Meeke and Julie A Schneider and Edwin Soriano and David A. Bennett},
  journal={Current Alzheimer research},
  year={2008},
  volume={5 1},
  pages={45-51}
}
Estrogen exerts beneficial effects on the brain throughout life. Studies demonstrate that estrogen is neuroprotective and that reduced brain estrogen activity may influence the clinical course of Alzheimer's disease (AD). Changes in levels of estrogen receptors have been detected in postmortem brain tissue of AD patients. Very little is known about the relationship between clinical stage and levels of estrogen receptors in postmortem brain. We hypothesized that estrogen receptor levels would be… CONTINUE READING

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