Levels of chromosomally encoded Umu proteins and requirements for in vivo UmuD cleavage

Abstract

Most of the inducible mutagenesis observed in Escherichia coli after treatment with many DNA damaging agents is dependent upon the products of the umuD,C operon. RecA-mediated proteolytic processing of UmuD yields a carboxyl-terminal fragment (UmuD′) that is active for mutagenesis. Processing of UmuD is therefore a critical step in the fixation of mutations… (More)
DOI: 10.1007/BF00264207

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@article{Woodgate1991LevelsOC, title={Levels of chromosomally encoded Umu proteins and requirements for in vivo UmuD cleavage}, author={Roger Woodgate and Don G. Ennis}, journal={Molecular and General Genetics MGG}, year={1991}, volume={229}, pages={10-16} }