Levels of cerebrospinal fluid α-synuclein oligomers are increased in Parkinson’s disease with dementia and dementia with Lewy bodies compared to Alzheimer’s disease

@inproceedings{Hansson2014LevelsOC,
  title={Levels of cerebrospinal fluid α-synuclein oligomers are increased in Parkinson’s disease with dementia and dementia with Lewy bodies compared to Alzheimer’s disease},
  author={Oskar Hansson and Sara Jane Hall and Annika {\"O}hrfelt and Henrik Zetterberg and K Blennow and Lennart Minthon and Katarina N{\"a}gga and Elisabet Y Londos and Shiji Varghese and Nour K. Majbour and Abdulmonem A. Al-Hayani and Omar M. A. El-Agnaf},
  booktitle={Alzheimer's Research & Therapy},
  year={2014}
}
The objective was to study whether α-synuclein oligomers are altered in the cerebrospinal fluid (CSF) of patients with dementia, including Parkinson disease with dementia (PDD), dementia with Lewy bodies (DLB), and Alzheimer disease (AD), compared with age-matched controls. In total, 247 CSF samples were assessed in this study, including 71 patients with DLB, 30 patients with PDD, 48 patients with AD, and 98 healthy age-matched controls. Both total and oligomeric α-synuclein levels were… CONTINUE READING

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Levels of cerebrospinal fluid α - synuclein oligomers are increased in Parkinson ' s disease with dementia and dementia with Lewy bodies compared to Alzheimer ' s disease

O. M. El-Agnaf
Alzheimer ' s Research & Therapy • 2014

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