Levels of beta-human chorionic gonadotropin in cerebrospinal fluid of patients with malignant germ cell tumor can be used to detect early recurrence and monitor the response to treatment.

@article{Fujimaki2000LevelsOB,
  title={Levels of beta-human chorionic gonadotropin in cerebrospinal fluid of patients with malignant germ cell tumor can be used to detect early recurrence and monitor the response to treatment.},
  author={Takamitsu Fujimaki and Kazuhiko Mishima and Akio Asai and Ken Tabuchi and Makio Kobayashi and Isamu Suzuki and Takaaki Kirino},
  journal={Japanese journal of clinical oncology},
  year={2000},
  volume={30 7},
  pages={291-4}
}
BACKGROUND Tumor marker-producing germ cell tumors of the central nervous system are malignant and require radiation and/or chemotherapy. Although serum beta-human chorionic gonadotropin (hCG) has been used to monitor the course of treatment, the levels of beta-hCG in the cerebrospinal fluid (CSF) have not been measured routinely in the clinic. To determine whether they can be used to evaluate parameters of tumor status, such as progression or response to therapy, levels of beta-hCG in the… CONTINUE READING

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