Levels of antibodies to Plasmodium falciparum sporozoite surface antigens reflect malaria transmission rates and are persistent in the absence of reinfection.

@article{Druilhe1986LevelsOA,
  title={Levels of antibodies to Plasmodium falciparum sporozoite surface antigens reflect malaria transmission rates and are persistent in the absence of reinfection.},
  author={Pierre L Druilhe and Olivier Pradier and Janja Marc and François Miltgen and Dominique Mazier and G Parent},
  journal={Infection and immunity},
  year={1986},
  volume={53 2},
  pages={393-7}
}
Antibodies reacting with Plasmodium falciparum sporozoite surface antigens were measured by an immunofluorescence assay using wet preparations of sporozoites attached to poly-L-lysine-treated glass slides, a procedure which was found to be more specific than one using glutaraldehyde-treated and dried preparations. Subjects recovering from a first attack were found to be negative. In two African villages which differed in the level at which mosquitoes transmit the disease (1 and 100 infective… CONTINUE READING
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