Levels of anti-M2 and anti-beta1 autoantibodies do not correlate with the degree of heart dysfunction in Chagas' heart disease.

@article{Talvani2006LevelsOA,
  title={Levels of anti-M2 and anti-beta1 autoantibodies do not correlate with the degree of heart dysfunction in Chagas' heart disease.},
  author={Andr{\'e} Talvani and Manoel {\'O}tavio da Costa Rocha and Ant{\^o}nio Luiz Pinho Ribeiro and Enri Borda and Leonor Sterin-Borda and Mauro M Teixeira},
  journal={Microbes and infection},
  year={2006},
  volume={8 9-10},
  pages={2459-64}
}
Chronic chagasic cardiomyopathy (CCC) is characterized mainly by a dilated cardiomyopathy complicated by frequent and complex ventricular arrhythmias and/or conduction defects. The aim of the present study was to evaluate functional implications of neurotransmitter receptor autoantibodies in vivo. Sera from chagasic patients were used to measure the level of autoantibodies to peptide fragments from the M2 cholinergic and beta1 adrenergic receptors. Optical density values and the frequency of… CONTINUE READING
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