Levels of GABAa receptor subunit mRNA in rat brain following flurazepam treatment.

Abstract

The regulation of the subunit composition of GABA(A) receptors may be a mechanism by which tolerance to the effects of benzodiazepines occurs. We have investigated this hypothesis by examining the levels of mRNA which codes for the GABA(A) β1, 2, 3 and γ2 subunits. Male Wistar rats were injected once daily with either flurazepam or vehicle, sacrificed after… (More)
DOI: 10.1177/026988119200600304

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Cite this paper

@article{ODonovan1992LevelsOG, title={Levels of GABAa receptor subunit mRNA in rat brain following flurazepam treatment.}, author={Michael C. O'Donovan and Paul R. Buckland and Peter McGuffin}, journal={Journal of psychopharmacology}, year={1992}, volume={6 3}, pages={364-9} }