Leveling up citizen science.

@article{Waldisphl2020LevelingUC,
  title={Leveling up citizen science.},
  author={J{\'e}r{\^o}me Waldisp{\"u}hl and Attila Szantner and Rob Knight and S{\'e}bastien Caisse and Randy Pitchford},
  journal={Nature biotechnology},
  year={2020}
}
Since 2008, the Foldit team has recruited online participants to predict protein 3D structure via a 3D puzzle game distributed as a standalone program for personal computers1. This project helped refine a retroviral protease structure2 and later discovered novel protein folds3. Two years later, Phylo4 pushed the gamification concept to reach a broader public by crowdsourcing comparative genomics tasks via tile-matching puzzle games. Other successful projects include web-based games for RNA… 

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References

SHOWING 1-10 OF 20 REFERENCES

De novo protein design by citizen scientists

TLDR
This work makes explicit the considerable implicit knowledge that contributes to success in de novo protein design, and shows that citizen scientists can discover creative new solutions to outstanding scientific challenges such as the protein design problem.

Predicting protein structures with a multiplayer online game

TLDR
Foldit is described, a multiplayer online game that engages non-scientists in solving hard prediction problems and shows that top-ranked Foldit players excel at solving challenging structure refinement problems in which substantial backbone rearrangements are necessary to achieve the burial of hydrophobic residues.

Phylo: A Citizen Science Approach for Improving Multiple Sequence Alignment

TLDR
Phylo, a human-based computing framework applying “crowd sourcing” techniques to solve the Multiple Sequence Alignment (MSA) problem, is introduced and it is demonstrated that, combined with classical algorithms, crowd computing techniques can be successfully used to help improving the accuracy of MSA.

Open-Phylo: a customizable crowd-computing platform for multiple sequence alignment

TLDR
Open-Phylo is introduced, a freely accessible crowd-computing platform that enables any scientist to enter the authors' system and use crowds of gamers to assist computer programs in solving one of the most fundamental problems in genomics: the multiple sequence alignment problem.

Deep learning is combined with massive-scale citizen science to improve large-scale image classification

TLDR
It is found that engaging players of commercial computer games provided data that augmented deep learning and enabled scalable and readily improved image classification, resulting in a boosted learner that can characterize subcellular protein distribution.

Crowd science user contribution patterns and their implications

TLDR
The findings inform recent discussions about potential benefits from crowd science, suggest that involving the crowd may be more effective for some kinds of projects than others, provide guidance for project managers, and raise important questions for future research.

American Gut: an Open Platform for Citizen Science Microbiome Research

TLDR
The utility of the living data resource and cross-cohort comparison is demonstrated to confirm existing associations between the microbiome and psychiatric illness and to reveal the extent of microbiome change within one individual during surgery, providing a paradigm for open microbiome research and education.

Crystal structure of a monomeric retroviral protease solved by protein folding game players

TLDR
Players of the protein folding game Foldit were able to generate models of sufficient quality for successful molecular replacement and subsequent structure determination of M-PMV retroviral protease, providing new insights for the design of antiretroviral drugs.

A communal catalogue reveals Earth’s multiscale microbial diversity

TLDR
A meta-analysis of microbial community samples collected by hundreds of researchers for the Earth Microbiome Project is presented, creating both a reference database giving global context to DNA sequence data and a framework for incorporating data from future studies, fostering increasingly complete characterization of Earth’s microbial diversity.

An Integrated Encyclopedia of DNA Elements in the Human Genome

TLDR
The Encyclopedia of DNA Elements project provides new insights into the organization and regulation of the authors' genes and genome, and is an expansive resource of functional annotations for biomedical research.