Level of scientific evidence underlying recommendations arising from the National Comprehensive Cancer Network clinical practice guidelines.

@article{Poonacha2011LevelOS,
  title={Level of scientific evidence underlying recommendations arising from the National Comprehensive Cancer Network clinical practice guidelines.},
  author={Thejaswi K Poonacha and Ronald S Go},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2011},
  volume={29 2},
  pages={186-91}
}
PURPOSE The level of scientific evidence on which the National Comprehensive Cancer Network (NCCN) guidelines are based has not been systematically investigated. We describe the distribution of categories of evidence and consensus (EC) among the 10 most common cancers with regard to recommendations for staging, initial and salvage therapy, and surveillance. METHODS NCCN uses a system of guideline development distinct from other major professional organizations. The NCCN definitions for EC are… CONTINUE READING
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