Level of expression of phospholipid scramblase regulates induced movement of phosphatidylserine to the cell surface.

@article{Zhao1998LevelOE,
  title={Level of expression of phospholipid scramblase regulates induced movement of phosphatidylserine to the cell surface.},
  author={J Zhao and Qiang Zhou and Therese Wiedmer and Peter J. Sims},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 12},
  pages={
          6603-6
        }
}
We recently identified a 35-kDa erythrocyte membrane protein, phospholipid scramblase, that promotes Ca2+-dependent transbilayer movement of phosphatidylserine (PS) and other phospholipids (PL) in reconstituted proteoliposomes (Zhou, Q., Zhao, J., Stout, J. G., Luhm, R. A., Wiedmer, T., and Sims, P. J. (1997) J. Biol. Chem. 272, 18240-18244). To determine whether this same protein is responsible for the rapid movement of PS from inner-to-outer plasma membrane leaflets in other cells exposed to… CONTINUE READING

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