Levamisole synergizes proliferation of intestinal IgA+ cells in weaned pigs immunized with vaccine candidate F4ac+ nonenterotoxigenic Escherichia coli strain.

@article{Janjatovi2008LevamisoleSP,
  title={Levamisole synergizes proliferation of intestinal IgA+ cells in weaned pigs immunized with vaccine candidate F4ac+ nonenterotoxigenic Escherichia coli strain.},
  author={Ana Kov{\vs}ca Janjatovi{\'c} and Gordana Lackovi{\'c} and Frane Bo{\vz}i{\'c} and Maja Popovi{\'c} and Ivica Valpoti{\'c}},
  journal={Journal of veterinary pharmacology and therapeutics},
  year={2008},
  volume={31 4},
  pages={328-33}
}
Levamisole (2, 3, 5, 6-tetrahydro-6-phenylimidazole 2,1-b thiazole) is a well-known nonspecific stimulator of host defence mechanisms. In previous investigations, we have found that levamisole acts on cell-mediated immunity in challenge-induced porcine postweaning colibacillosis (PWC). We assume that levamisole could also act synergistically on humoural immune response when applied as an adjuvant with vaccine candidate strains for oral immunization of weaned pigs against PWC. The influence of… CONTINUE READING