Levamisole in steroid-sensitive nephrotic syndrome: usefulness in adult patients and laboratory insights into mechanisms of action via direct action on the kidney podocyte.

@article{Jiang2015LevamisoleIS,
  title={Levamisole in steroid-sensitive nephrotic syndrome: usefulness in adult patients and laboratory insights into mechanisms of action via direct action on the kidney podocyte.},
  author={Lulu Jiang and Ishita Dasgupta and Jenny A. Hurcombe and Heather F Colyer and Peter William Mathieson and Gavin I. Welsh},
  journal={Clinical science},
  year={2015},
  volume={128 12},
  pages={883-93}
}
Minimal change nephropathy (MCN) is the third most common cause of primary nephrotic syndrome in adults. Most patients with MCN respond to corticosteroid therapy, but relapse is common. In children, steroid-dependent patients are often given alternative agents to spare the use of steroids and to avoid the cumulative steroid toxicity. In this respect, levamisole has shown promise due to its ability to effectively maintain remission in children with steroid-sensitive or steroid-dependent… CONTINUE READING