Levamisole: A Dangerous New Cocaine Adulterant

@article{Chang2010LevamisoleAD,
  title={Levamisole: A Dangerous New Cocaine Adulterant},
  author={Aimee Chang and John D. Osterloh and J. Thomas},
  journal={Clinical Pharmacology \& Therapeutics},
  year={2010},
  volume={88}
}
Levamisole has increasingly been discovered in street cocaine as an adulterant. Recent reports have linked levamisole in street cocaine to agranulocytosis in cocaine users. It is well known that agranulocytosis is associated with therapeutic use of levamisole, and this may have led to the withdrawal of the drug from the US market. Levamisole was a US Food and Drug Administration–approved drug that has been used as an immunomodulator, a chemotherapy adjuvant, and anthelmintic medication. The… 
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TLDR
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Cutaneous Necrotizing Vasculitis and Leukopenia in a Cocaine User: Is Levamisole the Culprit?
TLDR
A 23-year-old female cocaine user that presented with purpuric rash and skin necrosis, found to have positive c-ANCA and anti-proteinase 3 antibodies is reported, diagnosed with levamisole-induced vasculitis and successfully treated with withdrawal of cocaine use and local wound care.
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