Leukotrienes in Atherosclerosis: New Target Insights and Future Therapy Perspectives


Atherosclerosis represents an important chronic inflammatory process associated with several pathophysiological reactions in the vascular wall. The arachidonic acid, released by phospholipase A2, is an important substrate for the production of a group of lipid mediators known as leukotrienes, which induce proinflammatory signaling through the activation of… (More)
DOI: 10.1155/2009/737282


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