Leukotriene Signaling in Atherosclerosis and Ischemia

@article{Bck2008LeukotrieneSI,
  title={Leukotriene Signaling in Atherosclerosis and Ischemia},
  author={Magnus B{\"a}ck},
  journal={Cardiovascular Drugs and Therapy},
  year={2008},
  volume={23},
  pages={41-48}
}
IntroductionThe inflammatory process of atherosclerosis is associated with several pathophysiological reactions within the vascular wall. The arachidonic acid released by phospholipase A2 serves as substrate for the production of a group of lipid mediators known as the leukotrienes, which induce pro-inflammatory signaling through activation of specific BLT and CysLT receptors.DiscussionLeukotriene signaling has been implicated in early lipid retention and foam cell accumulation, as well as in… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 53 CITATIONS, ESTIMATED 51% COVERAGE

Study of arachidonoyl specificity in two enzymes of the PI cycle.

  • Journal of molecular biology
  • 2011
VIEW 7 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Dietary modulation of oxylipins in cardiovascular disease and aging.

  • American journal of physiology. Heart and circulatory physiology
  • 2017
VIEW 1 EXCERPT
CITES BACKGROUND

FILTER CITATIONS BY YEAR

2009
2019

CITATION STATISTICS

  • 3 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 75 REFERENCES

Leukotriene Receptors: Crucial Components in Vascular Inflammation

  • TheScientificWorldJournal
  • 2007
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

Inflammation, atherosclerosis, and coronary artery disease.

  • The New England journal of medicine
  • 2005
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Functional characteristics of cysteinyl-leukotriene receptor subtypes

M. Bäck
  • Life Sci
  • 2002
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1989
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

early mediator of atherosclerosis in obstructive sleep apnoea? Eur Respir J

B Lefebvre, JL Pepin, +4 authors B4 et al. Leukotriene
  • 2008;32:113–20. 46 Cardiovasc Drugs Ther
  • 2009
VIEW 3 EXCERPTS

Similar Papers