Leukotriene D(4) activates MAPK through a Ras-independent but PKCepsilon-dependent pathway in intestinal epithelial cells.

Abstract

We have recently shown that leukotriene D(4) (LTD(4)) increases cell survival in intestinal epithelial cells. Here we report and explore the complementary finding that LTD(4) also enhances proliferation in these cells. This proliferative response was approximately half of that induced by epidermal growth factor (EGF) and its required activation of protein… (More)

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Cite this paper

@article{Paruchuri2002LeukotrieneDA, title={Leukotriene D(4) activates MAPK through a Ras-independent but PKCepsilon-dependent pathway in intestinal epithelial cells.}, author={Sailaja Paruchuri and Bengt Hallberg and Maria Juhas and Christer Larsson and Anita Sj{\"{o}lander}, journal={Journal of cell science}, year={2002}, volume={115 Pt 9}, pages={1883-93} }