Leukotriene C4 produced by a human T-T hybridoma suppresses Ig production by human lymphocytes.

Abstract

Multiple signals are involved in the regulation of Ig production by human B lymphocytes. Leukotrienes, especially LTB4, have been shown to inhibit Ig production by increasing the number and function of suppressor lymphocytes. Production of leukotrienes has been demonstrated by mast cells, basophils, eosinophils, polymorphonuclear leukocytes, monocytes, and… (More)

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@article{Ambrus1988LeukotrieneCP, title={Leukotriene C4 produced by a human T-T hybridoma suppresses Ig production by human lymphocytes.}, author={Julian L Ambrus and Cynthia H Jurgensen and Nadine Witzel and Richard Alan Lewis and Joseph Butler and A. S. Fauci}, journal={Journal of immunology}, year={1988}, volume={140 7}, pages={2382-8} }