Leukotriene A4 hydrolase.

  title={Leukotriene A4 hydrolase.},
  author={Jesper Z. Haeggstr{\"o}m and Filippa Kull and Peter C Rudberg and Fredrik Tholander and Marjolein M. G. M. Thunnissen},
  journal={Prostaglandins & other lipid mediators},
The leukotrienes (LTs) are a family of lipid mediators involved in inflammation and allergy. Leukotriene B4 is a classical chemoattractant, which triggers adherence and aggregation of leukocytes to the endothelium at only nanomolar concentrations. In addition, leukotriene B4 modulates immune responses, participates in the host-defense against infections, and is a key mediator of PAF-induced lethal shock. Because of these powerful biological effects, leukotriene B4 is implicated in a variety of… CONTINUE READING
10 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…