Leukotoxic Activity of Aggregatibacter actinomycetemcomitans and Periodontal Attachment Loss

@inproceedings{berg2014LeukotoxicAO,
  title={Leukotoxic Activity of Aggregatibacter actinomycetemcomitans and Periodontal Attachment Loss},
  author={C H{\"o}glund {\AA}berg and Dorte Haubek and Francis Kwamin and Anders F Johansson and Rolf Claesson},
  booktitle={PloS one},
  year={2014}
}
  • C Höglund Åberg, Dorte Haubek, +2 authors Rolf Claesson
  • Published in PloS one 2014
  • Biology, Medicine
  • Aggregatibacter actinomycetemcomitans is a Gram-negative periodontitis-associated bacterium that expresses a toxin that selectively affects leukocytes. This leukotoxin is encoded by an operon belonging to the core genome of this bacterial species. Variations in the expression of the leukotoxin have been reported, and a well-characterized specific clonal type (JP2) of this bacterium with enhanced leukotoxin expression has been isolated. In particular, the presence of the JP2 genotype… CONTINUE READING

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