Leukodepletion of autologous whole blood has no impact on perioperative infection rate and length of hospital stay.

@article{Frietsch2008LeukodepletionOA,
  title={Leukodepletion of autologous whole blood has no impact on perioperative infection rate and length of hospital stay.},
  author={Thomas Frietsch and R. Karger and Michael Sch{\"o}ler and Daniela Huber and Thomas Bruckner and Volker Kretschmer and Susanne Schmidt and Werner Leidinger and Arnulf Weiler-Lorentz},
  journal={Transfusion},
  year={2008},
  volume={48 10},
  pages={2133-42}
}
BACKGROUND Several mechanisms have been proposed as possible causes of transfusion-related immunomodulation (TRIM) after allogeneic transfusion. If one of these mechanisms, the release of mediators of immunity and inflammation ("biologic response modifiers"[BRMs]) from disintegrating blood cells during storage of blood products, really causes TRIM, it should in principle also occur after autologous transfusion. As a consequence, prestorage leukoreduction of autologous blood should be able to… CONTINUE READING