Leukocytosis-promoting factor of Bordetella pertussis. 3. Its identity with protective antigen.


Leukocytosis-promoting factor (LPF) was purified from the supernatant of a 5-day liquid culture of Bordetella pertussis strains Tohama and no. 134. The preparations appeared to be filamentous molecules (2 by 40 nm) and contained histamine-sensitizing and hemagglutinin activities in addition to leukocytosis-promoting activity. Active protection tests in mice… (More)

8 Figures and Tables


  • Presentations referencing similar topics