Leukocytes contribute to hepatic ischemia/reperfusion injury via intercellular adhesion molecule-1-mediated venular adherence.

@article{Vollmar1995LeukocytesCT,
  title={Leukocytes contribute to hepatic ischemia/reperfusion injury via intercellular adhesion molecule-1-mediated venular adherence.},
  author={Brigitte Vollmar and J. Glasz and Michael Dieter Menger and K. Me\ssmer},
  journal={Surgery},
  year={1995},
  volume={117 2},
  pages={195-200}
}
BACKGROUND Leukocytes are suggested to modulate ischemia/reperfusion injury via membrane receptor-controlled interaction with the microvascular endothelium. METHODS With the use of intravital fluorescence microscopy we investigated the role of the intercellular adhesion molecule-1 (ICAM-1) in a rat model of hepatic reperfusion injury with a neutralizing monoclonal antibody (anti-ICAM-1). RESULTS Sixty minutes of left lobar ischemia and reperfusion (isotype-matched immunoglobulin G1 control… CONTINUE READING
48 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 48 extracted citations

Similar Papers

Loading similar papers…