Leukocyte transcellular diapedesis: Rap1b is in control.


The neutrophil transmigration across the blood endothelial cell barrier represents the prerequisite step of innate inflammation. It is well known that neutrophils cross the endothelial barrier by transmigrating at the endothelial cell junction ('paracellular'). However, in vivo and in vitro evidence have clearly demonstrated occurrence of an alternate mode… (More)
DOI: 10.1080/21688370.2015.1052185