Leukocyte presence does not increase microbicidal activity of Platelet-rich Plasma in vitro

  title={Leukocyte presence does not increase microbicidal activity of Platelet-rich Plasma in vitro},
  author={Erminia Mariani and Valentina Canella and Andrea Berlingeri and Alessandra Bielli and Luca Cattini and Maria Paola Landini and Elizaveta Kon and Maurilio Marcacci and Berardo Di Matteo and Giuseppe Filardo},
  booktitle={BMC Microbiology},
Human platelets are a rich reservoir of molecules that promote regenerative processes and microbicidal activity. This activity might be increased by concentration in platelet-rich plasma (PRP) products and modulated by the presence of leukocytes. Despite extensive use in clinical procedures, only few studies have investigated PRP’s real microbicidal potential. Therefore, this study aimed at comparing the in vitro microbicidal activity of platelets and leukocyte-enriched PRP (L-PRP) to pure… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 6 times. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.


Publications referenced by this paper.
Showing 1-10 of 53 references

Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.

Journal of leukocyte biology • 2003
View 5 Excerpts
Highly Influenced

defining a role for IL-6

Jones SA. Directing transition from innate to acquired immunity
J Immunol. 2005;175:3463–8. Mariani et al. BMC Microbiology • 2015
View 1 Excerpt

the ancient arm of the human immune system

J Wiesner, Vilcinskas A. Antimicrobial peptides
Virulence. 2010;1:440–64. Mariani et al. BMC Microbiology • 2015
View 3 Excerpts

Comparison of platelet-rich plasma formulations for cartilage healing: an in vitro study.

The Journal of bone and joint surgery. American volume • 2014
View 1 Excerpt

Effect of two different preparations of platelet-rich plasma on synoviocytes

Knee Surgery, Sports Traumatology, Arthroscopy • 2014
View 1 Excerpt

Similar Papers

Loading similar papers…