Leukocyte-derived microparticles in vascular homeostasis.

  title={Leukocyte-derived microparticles in vascular homeostasis.},
  author={Anne Angelillo-Scherrer},
  journal={Circulation research},
  volume={110 2},
Leukocyte-derived microparticles (LMPs) may originate from neutrophils, monocytes/macrophages, and lymphocytes. They express markers from their parental cells and harbor membrane and cytoplasmic proteins as well as bioactive lipids implicated in a variety of mechanisms, maintaining or disrupting vascular homeostasis. When they carry tissue factor or coagulation inhibitors, they participate in hemostasis and pathological thrombosis. Both proinflammatory and anti-inflammatory processes can be… CONTINUE READING


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