Leukocyte count as a predictor of death during remission induction in acute myeloid leukemia.

@article{Greenwood2006LeukocyteCA,
  title={Leukocyte count as a predictor of death during remission induction in acute myeloid leukemia.},
  author={Matthew J Greenwood and Matthew D. Seftel and Carol E. Richardson and Draga Barbaric and Michael Barnett and H{\'e}l{\`e}ne Bruy{\`e}r{\`e} and Donna L. Forrest and Douglas E. Horsman and Clayton Smith and Kevin W. Song and Heather J. Sutherland and Cynthia L Toze and Thomas J. Nevill and Stephen H Nantel and Donna Hogge},
  journal={Leukemia & lymphoma},
  year={2006},
  volume={47 7},
  pages={1245-52}
}
Acute myeloid leukemia (AML) presenting with a high leukocyte count has been associated with an increase in induction mortality and poor results in a number of other survival measures. However, the level at which an elevated leukocyte count has prognostic significance in AML remains unclear. In this report on a series of 375 adult (non-M3) AML patients undergoing induction chemotherapy at a single institution, leukocyte count analyzed as a continuous variable is shown to be a better predictor… CONTINUE READING