Leukocyte common antigen-related receptor-linked tyrosine phosphatase. Regulation of mRNA expression.

@article{Longo1993LeukocyteCA,
  title={Leukocyte common antigen-related receptor-linked tyrosine phosphatase. Regulation of mRNA expression.},
  author={Frank M Longo and John A. Martignetti and J M Le Beau and Julie S Zhang and Jane P. Barnes and J{\"u}rgen Brosius},
  journal={The Journal of biological chemistry},
  year={1993},
  volume={268 35},
  pages={26503-11}
}
Receptor-linked tyrosine phosphatases regulate cell growth by dephosphorylating proteins involved in tyrosine kinase signal transduction. Within this gene family, the leukocyte common antigen-related (LAR) gene is of particular interest with respect to the nervous system because it has sequence similarity to the neural cell adhesion molecule N-CAM and is located in a chromosomal region (1p32-33) frequently deleted in neuroectodermal tumors. However, immunostaining has detected LAR in non-neural… CONTINUE READING
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