Leukocyte- and platelet-derived microparticles correlate with thrombus weight and tissue factor activity in an experimental mouse model of venous thrombosis.

@article{Ramacciotti2009LeukocyteAP,
  title={Leukocyte- and platelet-derived microparticles correlate with thrombus weight and tissue factor activity in an experimental mouse model of venous thrombosis.},
  author={Eduardo Ramacciotti and Angela E. Hawley and Diana M. Farris and Nicole E Ballard and Shirley K. Wrobleski and Daniel Myers and Peter K. Henke and Thomas W. Wakefield},
  journal={Thrombosis and haemostasis},
  year={2009},
  volume={101 4},
  pages={
          748-54
        }
}
  • Eduardo Ramacciotti, Angela E. Hawley, +5 authors Thomas W. Wakefield
  • Published in Thrombosis and haemostasis 2009
  • Medicine
  • Microparticles (MP) are lipid vesicles from platelets, leukocytes and endothelial cells that are involved in early thrombogenesis. We evaluated a detailed time-course analysis of MPs on thrombogenesis and the associated tissue factor (TF) activity in wild-type, in gene-deleted for E- and P-selectins and with high levels of P-selectin expression after the initiation of venous thrombosis in mice. Inferior vena cava (IVC) ligation was performed on C57BL/6 mice (n = 191, 59 = wild-type [WT], 55… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 58 CITATIONS, ESTIMATED 40% COVERAGE

    Biology and Role of Extracellular Vesicles (EVs) in the Pathogenesis of Thrombosis

    VIEW 4 EXCERPTS
    CITES BACKGROUND & METHODS
    HIGHLY INFLUENCED

    FILTER CITATIONS BY YEAR

    2009
    2019

    CITATION STATISTICS

    • 2 Highly Influenced Citations