Leukocyte-Reduced Platelet-Rich Plasma Normalizes Matrix Metabolism in Torn Human Rotator Cuff Tendons.

@article{Cross2015LeukocyteReducedPP,
  title={Leukocyte-Reduced Platelet-Rich Plasma Normalizes Matrix Metabolism in Torn Human Rotator Cuff Tendons.},
  author={Jessica A Cross and Brian Cole and Kaylan P Spatny and Emily A Sundman and Anthony A Romeo and Greg P Nicholson and Bettina Wagner and Lisa A Fortier},
  journal={The American journal of sports medicine},
  year={2015},
  volume={43 12},
  pages={2898-906}
}
BACKGROUND The optimal platelet-rich plasma (PRP) for treatment of supraspinatus tendinopathy has not been determined. PURPOSE To evaluate the effect of low- versus high-leukocyte concentrated PRP products on catabolic and anabolic mediators of matrix metabolism in diseased rotator cuff tendons. STUDY DESIGN Controlled laboratory study. METHODS Diseased supraspinatus tendons were treated with PRP made by use of 2 commercial systems: Arthrex Autologous Conditioned Plasma Double Syringe… CONTINUE READING
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