Leukocytapheresis in pediatric patients with ulcerative colitis.

  title={Leukocytapheresis in pediatric patients with ulcerative colitis.},
  author={Takeshi Tomomasa and Hitoshi Tajiri and Seiichi Kagimoto and Toshiaki Shimizu and Atsushi Yoden and Kosuke Ushijima and Keiichi Uchida and Hiroaki Kaneko and Daiki Abukawa and Mutsuko Konno and Shun-ichi Maisawa and Takao Kohsaka and Akio Kobayashi},
  journal={Journal of pediatric gastroenterology and nutrition},
  volume={53 1},
OBJECTIVE Leukocytapheresis (LCAP) is a nonpharmacologic therapy that has recently been used to treat ulcerative colitis (UC). This multicenter open-label study prospectively assessed the efficacy and safety of LCAP in pediatric patients with UC. PATIENTS AND METHODS Twenty-three patients ages 8 to 16 years with moderate (n = 19) to severe (n = 4) steroid-resistant UC were enrolled. One of 2 LCAP columns with different volumes (model EX and the half-volume model EI) was selected, according to… CONTINUE READING
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