Leukemic involvement of the optic nerve.

@article{Nikaido1988LeukemicIO,
  title={Leukemic involvement of the optic nerve.},
  author={Hiroko Nikaido and Hiroshi Mishima and Hironori Ono and Kanji Choshi and Hiroo Dohy},
  journal={American journal of ophthalmology},
  year={1988},
  volume={105 3},
  pages={
          294-8
        }
}
We studied five cases of leukemia with invasion of the optic disk and optic nerve. Two patients had acute lymphoblastic leukemia and three had acute myelogenous leukemia. All patients received intrathecal injections of chemotherapeutic drugs including methotrexate, cytarabine, and prednisolone. Three patients underwent irradiation therapy of the whole brain and optic nerve. While initial improvement in the ophthalmic abnormalities, such as optic disk edema, flame-shaped retinal hemorrhages, and… CONTINUE READING

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